By D. Virgil Alfaro III MD, Peter E. Liggett MD, William F. Mieler MD, Hugo Quiroz-Mercado MD, Rama D. Jager MD MBA FACS, Yasuo Tano MD
A popular team of retina surgeons offers promising new advancements in age-related macular degeneration, with emphasis at the most vital advances long ago 5 years. content material addresses all points of administration, together with anatomy, body structure, and pathophysiology; imaging of the macula in age-related macular degeneration; prevention measures and therapy; remedy; and destiny instructions. Abundantly illustrated and fantastically prepared, this booklet serves as a superb reference and textbook.
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Additional info for Age-Related Macular Degeneration: A Comprehensive Textbook
GCL, ganglion cell layer; ILM, internal limiting membrane; IPL, inner plexiform layer; V, vitreous (original magnification ×100). (Reprinted with permission from Smith LEH, Wesolowski E, McLellan A, et al. Oxygen-induced retinopathy in the mouse. Invest Opthalmol Vis Sci. 19 closed colony of semi-free-ranging rhesus monkeys that have been maintained in isolation since 1938 by the Caribbean Primate Research Center (CPRC) (87,88). The animals were examined by ophthalmoscopy, fundus photography, and fluorescein angiography.
2 Accumulation of lipids in Bruch's membrane as a potential cause of CNV in ARMD. Although the diffusion of growth factors secondary to lipid accumulation in Bruch's membrane has been proposed as a potential cause of CNV, the exact mechanism by which this is supposed to occur has not been defined. Histologic evaluation of choriocapillaris in aging eyes by Ramrattan et al. 26 vascular density. , eyes with ARMD showed fewer large choroidal vessels in the submacular choroid and a higher density of the submacular choriocapillaris than controls without ARMD (65).
1985;103:708-711. 36. Miller JW, Walsh AW, Kramer M, et al. Photodynamic therapy of experimental choroidal neovascularization using lipoproteindelivered benzoporphyrin. Arch Ophthalmol. 1995;113:810-818. 18. Penforld P, Killingsworth M, Sarks S. An ultrastructural study of the role of leucocytes and fibroblasts in the breakdown of Bruch's membrane. Aust J Ophthalmol. 1984;12:23-31. 37. Kramer M, Miller JW, Michaud N, et al. Liposomal benzoporphyrin derivative verteporfin photodynamic therapy. Selective treatment of choroid neovascularization in monkeys.